Item(s) added to cart

Item(s) not added to cart

Epimune Complex

  • Gluten Free
  • Vegetarian

Introduced in 2009

Product # Content Price
4050 90 Capsules $69.50

Epimune Complex is a vegetarian immune system support designed to balance immune system response function.

  • Supports specific aspects of immune system activity and contains research-supported ingredients such as EpiCor® and maitake and turkey tail mushrooms
  • Supports healthy white blood cells
  • Helps support respiratory health year-round, especially during seasonal challenges
  • Helps activate and balance a healthy immune system response function
  • High in antioxidant vitamin C*

Gluten FreeThis product contains less than 20 parts per million per the suggested use listed on each product label.

VegetarianVegetarian (lacto-ovo)

Please consult the actual product label for the most accurate product information.


Show Studies 

Studies on nutrients generally use large doses and these studies, some of which are cited below, are the basis for much of the information we provide you in this publication about whole food ingredients. See the supplement facts for Epimune Complex.

  1. Patel S, Goyal A. 2012.. 3 Biotech. 2(1): 1–15.
  2. Adachi Y, Suzuki Y, Ohno N, Yadomae T. 1998. Adjuvant effect of grifolan on antibody production in mice. Biol Pharm Bull. 21(9):974-977.
  3. Alpert P.T. 2013. Calcium, a necessary mineral for proper body function: Facts you should know. Home Health Care Mgt Practice 25:239-241
  4. Deng G, Lin H, Seidman A, et al. 2009. J Cancer Res Clin Oncol. 135(9):1215-21.
  5. Engelbrecht K, Volk T. Ganoderma lucidum, Reishi or Ling Zhi, a fungus used in Oriental medicine. 2005; Accessed August 25, 2009: View Study.
  6. Fisher DW. David Fischer‘s American Mushrooms. 2007; Accessed August 14, 2009: View Study.
  7. Hong L, Xun M, Wutong W. 2007. Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice. J Pharm Pharmacol. 59(4):575-582.
  8. Jeong SC, Yang BK, GN K, et al. 2006. Macrophage-stimulating activity of polysaccharides extracted from fruiting bodies of Coriolus versicolor (Turkey Tail Mushroom). J Med Food. 9:175-181.
  9. Kodama N, Murata Y, Nanba H. 2004. Administration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice. J Med Food. 7(2):141-145.
  10. Li X, Rong J, Wu M, Zeng X. 2003. Anti-tumor effect of polysaccharide from Grifola frondosa and its influence on immunological function. Zhong Yao Cai. 26(1):31-32.
  11. Maggini S, Wintergerst E, Beveridge S, Hornig D. 2007. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune repsonses. Br J Nutr. 98(Supppl 1):S29-S35.
  12. Mizuno T, C. Z. Maitake. 1995. Grifola frondosa: pharmacological effects. Special Issue 11(1): 135 - 149.
  13. Moyad MA, Robinson LE, Zawada ET, Jr., et al. 2008. Effects of a modified yeast supplement on cold/flu symptoms. Urol Nurs. 28(1):50-55.
  14. Ohno N, Egawa Y, Hashimoto T, Adachi Y, Yadomae T. 1996. Effect of beta-glucans on the nitric oxide synthesis by peritoneal macrophage in mice. Biol Pharm Bull. 19(4):608-612.
  15. Robinson L, Reeves S. Summary of Human Clinical Trials on EpiCor; 2008. Accessed May 17, 2015. View Study
  16. Sanzen I, Imanishi N, Takamatsu N, et al. 2001. Nitric oxide-mediated antitumor activity induced by the extract from Grifola frondosa (Maitake mushroom) in a macrophage cell line, RAW264.7. J Exp Clin Cancer Res. 20(4):591-597.
  17. Schauss AG, Vojdani, A. 2006. Discovery of edible fermentation product with unusual immune enhancing properties in humans. FASEB J. 20(A143). Shen-Nong. Ganoderma. 2005; Accessed August 25, 2009: View Study.
  18. Shen-Nong Ltd. Coriolus versicolor. 2006; Accessed August 14, 2009: View Study.
  19. Suzuki I, Hashimoto K, Oikawa S, Sato K, Osawa M, Yadomae T. 1989. Antitumor and immunomodulating activities of a beta-glucan obtained from liquid-cultured Grifola frondosa. Chem Pharm Bull (Tokyo). 37(2):410-413.
  20. U.S. Food and Drug Administration. Dietary Supplement Fact Sheet: Zinc. 2009; Accessed August 26, 2009: View Study.
  21. Volk T, Zitomer N. Grifola frondosa, the Hen of the Woods, a.k.a. Sheepshead or Maitake November, 2006; Accessed August 14, 2009: View Study.
  22. Weaver CM, Heaney, R.P. 1999. Modern Nutrition in Health and Disease. In: Shils M, Olson, JA, Shike, M, Ross, AC, ed. 9th ed. ed. Baltimore: Williams & Wilkins; 141-155.
  23. Yu S, Weaver V, Martin K, Cantorna M. 2009. The effects of whole mushrooms during inflammation. BMC Immunol. 20(10).

Whole Food Nutrient Solutions

Since 1929, Standard Process has been the visionary leader in whole food nutrient solutions. We apply systems thinking to holistic nutrition that empowers practitioners to transform lives. Dedicated to the whole food philosophy of our founder, Dr. Royal Lee, our goal is to carry on his mission to provide nutrients for the body that are as close as possible to how they are found in nature.

Our products include foods that are prepared in a way that safeguards their nutritional value. The majority of these ingredients are grown locally on our certified organic farm and may require chopping, dicing, juicing and/or drying for use in our products. The resulting whole food ingredients are then added to a formula that may include whole food extracts, animal tissue extracts and concentrates, botanicals, whole food isolates and synthetic ingredients. These highly complex combinations contain a variety of elements designed to trigger trophic effects that support the body’s healthy balance and wellness.*


Suggested Use: Two capsules per day, or as directed.

Supplement Facts
Serving Size: 2 Capsules Servings per Container: 45
Amount per Serving %Daily Value
Calories 4  
Vitamin C 20 mg 30%
Calcium 30 mg 2%
Zinc 10 mg 60%

Proprietary blend amount: 706 mg

Dried yeast fermentate (EpiCor®)†, turkey tail mushroom powder†, maitake mushroom powder†, and maitake mushroom extract (Maitake Gold 404)†.

*Percent Daily Values (DV) based on a 2,000 calorie diet.

†Daily Value not established.

Other Ingredients: Calcium lactate, cellulose, zinc rice chelate, acerola (berry), and manioc (root)†.

Please consult the actual product label for the most accurate product information.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.