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Omega-3 Supplements

For Foundational and Condition-Specific Support

Balance: An Improved Ratio of Omega-3 to Omega-6

The body needs a higher ratio of omega-3 to omega-6 to support the resolution phase of the inflammation process.1 Currently, the Standard American Diet is high in omega-6 fatty acids and low in omega-3s, up to the ratio of 20:12 which can tip a healthy body system out of balance and allow low levels of inflammation to occur.

Eicosapentaenoic (EPA) & Docosahexaenoic (DHA)

While foundational omega-3 supplementation is typically used to maintain general health, concentrated EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), like our Olprima products, are better positioned to provide condition-specific support and can be used by patients for a duration as directed by a health care professional.

A Full Family of Omega-3 Oils

Standard Process offers omega-3 solutions for foundational needs as well as concentrated doses to help target condition-specific needs for a healthy body. There are three main types of omega-3 oils: EPA, DPA, and DHA each of which play important roles in maintaining a healthy body.7,8,9 They work individually and can also be combined with more targeted ratios to address condition-specific needs.1,10

When used at the optimal ratio and dose, concentrated DHA and/or EPA may improve specific clinical conditions in very different ways from foundational omega-3 supplementation typically used to maintain good health. Standard Process now offers a range of targeted formulations of EPA and DHA to address a variety of health needs.

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Condition-Specific Support

Olprima™ concentrated omega-3 oils provide targeted support for condition-specific needs related to cardiovascular health, brain health, and a healthy inflammatory process.

Rigorously Tested

Sustainably Sourced


Olprima™ DHA

Olprima™ EPA

Olprima™ EPA l DHA

Foundational Support

Supports general health and helps to bridge the gap in dietary omega-3 intake

Calamari Omega-3 Liquid

Tuna Omega-3 Chewable

Tuna Omega-3 Oil

Cod Liver Oil

Omega-3s Support Wellness, Cardiovascular Health, and Brain Health

Omega-3s are polyunsaturated fatty acids (PUFAs) that play critical roles in the human body and are particularly abundant in the brain and retina. These PUFAs and their metabolites regulate a number of important body systems on a cellular level, including cardiovascular, pulmonary, immune, nervous3, and endocrine systems.4,5

On-Demand Webinar for Practitioners

The Need for Balance:

Using Foundational and Targeted Omega-3 Supplementation in Your Practice

A Large Percentage of the U.S. Adult Population Falls Below the Recommendation for Omega-3 Intake

EPA and DHA Omega-3 Supplement Benefits for Foundational & Condition-Specific Support 
The American Heart Association recommends eating at least two servings of 3.5 ounces of fish per week to help maintain cardiovascular health.6 While these essential fatty acids are key in helping the body to run smoothly, our bodies do not produce them efficiently, and therefore it is recommended that they be consumed at higher levels in the diet.


Omega-3s, short for omega-3 fatty acids, is a family of essential fatty acids that play important roles in the human body. Since EPA and DHA are not made efficiently by the body, it is recommended that these be consumed at higher levels in the diet. Omega-3 fatty acids are polyunsaturated fatty acids (PUFAs), meaning that they have several double bonds in the chemical structure. Omega-3s include alpha-linolenic acid (ALA), docosahexaenoic acid (DHA), Eicosapentaenoic acid (EPA) and the less known docosapentaenoic acid (DPA). ALA mainly is found in plants, while DHA and EPA are mainly found in animal foods and algae,

EPA is associated with a positive effect on emotional balance. Just fifteen percent of ALA turns into EPA, and even a smaller amount is eventually converted to DHA. DHA is the most abundant omega-3 in the brain. It is a major component of the neuronal membrane and plays an important role in normal brain structure. Both EPA and DHA are precursors for pro-resolving mediators that biosynthesized to resolvins, protectins, and maresins which are named for their role in resolving the inflammatory response.

Omega-3s play critical roles in the human body and are abundant in the brain and retina. These essential fatty acids and their metabolites regulate a number of body systems including cardiovascular, pulmonary, immune, nervous, and endocrine systems. Omega-3s are components of the phospholipid structures of the cell membrane and are important for cell membrane structure stability and fluidity. Phospholipids are also a good source of energy and play a role in cell signaling. In short, like oil for any machine, omega-3s help the body operate smoothly.

Omega-3 fatty acids are needed for optimal function of the human body, and they may also provide numerous powerful health benefits. Scientific evidence from several clinical intervention studies has shown that adequate intake of omega-3 fatty acids is associated with several beneficial health outcomes. An emerging number of clinical studies have investigated the actions of EPA, DPA and DHA individually rather than together. It is now possible to tailor different blends of individual omega-3s, mainly EPA and DHA, according to the health benefits we are seeking to achieve.

Standard Process offers a range of targeted formulations of EPA and DHA for a variety of health benefits. Foundational forms of omega-3 supplementation include Calamari Omega-3 Liquid, Tuna Omega-3 OilTuna Omega-3 Chewable, and Cod Liver Oil, which each help to bridge the gap of omega-3 intake and support general health. Our three Olprima products -- Olprima EPA, Olprima DHA, and Olprima EPA|DHA -- are concentrated omega-3 oils, which can provide condition specific support and can be used by patients for a duration as directed by their health care practitioner.

Our Olprima products are concentrated omega-3 oils. They offer various concentrations of the omega-3 oils with an emphasis on purified EPA, DHA or a combination of EPA and DHA. The intent is to offer a concentrated therapeutic dose of targeted omega-3s. All Olprima products join our current omega-3 products in being gluten-free, sustainably-sourced and pure.

For more information, please contact the Standard Process Customer Care at:

Phone: 800-558-8740

Complementary Educational Tools

Omega-3 Patient Presentation


Olprima DHA Fact Sheet


Olprima EPA Fact Sheet


Olprima EPA | DHA Fact Sheet


Calamari Omega-3 Oil Fact Sheet


Cod Liver Oil Fact Sheet


Olprima™ Flyer


1.  Innes, J.K. & Calder, P.C. The Differential Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Cardiometabolic Risk Factors: A Systematic Review. Int J Mol Sci 19(2018).

2.  Simopoulos (2016) An increase in Omega6, omega3 FA ratio risk obesity nutrients-08-00128.

3. Dyall, S.C. Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA, and DHA.Front Aging Neurosci 7, 52 (2015).

4. van Gelder, B.M., Tijhuis, M., Kalmijn, S. & Kromhout, D. Fish consumption, n-3 fatty acids, and subsequent 5-y cognitive decline in elderly men: the Zutphen Elderly Study. Am J Clin Nutr 85, 1142-1147 (2007).

5. SanGiovanni, J.P. & Chew, E.Y. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res 24, 87-138 (2005). 

6. (2019). Fish and Omega-3 Fatty Acids. [online] Available at:

7. Dangardt, F., et al. Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents. Atherosclerosis 212, 580-585 (2010).

8. Agriculture., U.S.D.o.H.a.H.S.a.U.S.D.o. 2015 – 2020 Dietary Guidelines for Americans. (ed. Agriculture., U.S.D.o.H.a.H.S.a.U.S.D.o.) (2015).

9. Allaire, J., et al. A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study. Am J Clin Nutr 104, 280-287 (2016). 

10. Mozaffarian, D. & Wu, J.H. (n-3) fatty acids and cardiovascular health: are effects of EPA and DHA shared or complementary? J Nutr 142, 614S-625S (2012).

^as part of a diet low in saturated fat and cholesterol.