Item(s) added to cart

Item(s) not added to cart

The Standard Process Research and Development Team generates high-quality research through cell, animal, and human studies, to expand our knowledge of how complex mixtures, like supplements made with whole food ingredients, support health.


Innovation Is Our Standard

Leading clinical innovation has been the focus of Standard Process for nearly 90 years. Today this commitment continues with the Standard Process Center of Excellence.

The center is designed to deliver new clinical advances and insights in nutrition therapy. A dedicated innovation center, the facility includes a range of research and development activity encompassing discovery of new natural health solutions, clinical development, product development, food science, and even the industry’s only dedicated media learning facility for practitioner education.

Opening in November 2017, the Center of Excellence is located at the prestigious North Carolina Research Campus in Kannapolis, North Carolina, and will be led by John Troup, PhD, Standard Process vice president of clinical science, education, and innovation. The Standard Process facility is the only innovation and clinical research center of its kind in the nutrition industry, being fully dedicated to supporting the needs of natural health care professionals by focusing on clinical outcomes in therapeutic care as well as specific benefits and outcomes of whole food clinical nutrition. The center will serve as an active site that advances holistic, integrative, and functional medicine for all practitioners.

The center’s work will bring forward the legacy of our first innovator, Standard Process founder Dr. Royal Lee, by advancing clinical practices based on the whole food health advantage.

Center of Excellence

The Center of Excellence will house four major program functions, including:

  1. Discovery innovation research focused on preclinical, systems biology, and cell models that advance information on targeted effects of phytonutrients and nutritional solutions
  2. A clinical development and research program defined by a national coalition of collaborating clinical research sites that establishes a network for practice-based and case-observation studies conducted on a national basis
  3. A professional media and learning center that will provide the most advanced educational tools and capabilities available to advance practitioner education and training
  4. The Clinic of the Future, an integrative clinical practice bringing together multiple credentialed health professionals at one site

Look for more information soon about the Center of Excellence as the official opening approaches.

Read Press Release

Clinical Research

We design, conduct, and fund human research to expand knowledge of how complex mixtures (like whole foods) support health. We work with academic, medical, and contract research organizations to establish the activity of Standard Process® supplements in healthy human subjects.

View More

Discovery Science

We use the latest instrumentation and laboratory techniques to analyze products and raw materials for internal decision making and external publication of results in peer-reviewed journals.

View More

Are you interested in collaborating on research?

We are too! Please send us your qualifications and provide:
  • Topic of interest along with a brief explanation
  • Contact information
Contact Us

Published Research

  1. Plos One. 2015 Sept; OI:10.1371/journal.pone.0138275 Survival and Diversity of Human Homologous Dietary MicroRNAs in Conventionally Cooked Top Sirloin and Dried Bovine Tissue Extracts. Dever JT, Kemp MQ, Thompson AL, Keller HGK, Waksmonski JC, Scholl CD, Barnes DM.
  2. BMC Complement Altern Med. 2014;14:43. A double-blind, randomized clinical trial of dietary supplementation on cognitive and immune functioning in healthy older adults. Lewis JE, Melillo AB, Trozzo E, Chen L, Leonard S, Howell M, Diaz J, Gonzalez K, Woolger JM, Konefal J, Paterson E, Barnes DM.
  3. BMC Complement Altern Med. 2014;14:475. An open label pilot study to evaluate the efficacy of Spanish black radish on the induction of phase I and phase II enzymes in healthy male subjects</a>. Evans M, Paterson E, Barnes DM.
  4. Nutr Cancer. 2012 Oct;64(7):1038-4. Spanish Black Radish (Raphanus Sativus l. var. niger) Diet Enhances Clearance of DMBA and Diminishes Toxic Effects on Bone Marrow Progenitor Cells. N'jai AU, Kemp MQ, Metzger BT, Hanlon PR, Robbins M, Czuyprynski C, Barnes DM.
  5. Brandon T. Metzger. 2012 March 6. Chapter 10: "Carrot Bisacetylenic Oxylipins - Phytochemicals Behind the Mask of the Superfood" in Emerging Trends in Dietary Components for Preventing and Combating Disease, American Chemical Society, ACS Symposium Series Vol. 1093; 167-184.
  6. J Food Sci. 2011 Apr;76(3):C454-61. doi: 10.1111/j.1750-3841.2011.02105.x. Heat treatment of Brussels sprouts retains their ability to induce detoxification enzyme expression in vitro and in vivo. Robbins MG, Andersen G, Somoza V, Eshelman BD, Barnes DM, Hanlon PR.
  7. J Food Sci. 2011 Apr;76(3):C504-11. doi: 10.1111/j.1750-3841.2011.02078.x. Epub 2011 Mar 21.Raphasatin is a more potent inducer of the detoxification enzymes than its degradation products. Scholl C, Eshelman BD, Barnes DM, Hanlon PR.
  8. J Food Sci. 2011 Jan-Feb;76(1):C185-92. doi: 10.1111/j.1750-3841.2010.01972.x. Phytochemical composition and biological activity of 8 varieties of radish (Raphanus sativus L.) sprouts and mature taproots. Hanlon PR, Barnes DM.
  9. J Herbs Spices Med Plants 2010 Aug 16:106-118. Longitudinal expression of antioxidant phytochemicals in buckwheat (Fagopyrum esculentum Moench). Metzger BT, Robbins MG, Barnes DM
  10. J Food Sci. 2010 Aug 1;75(6):H190-9. Induction of detoxification enzymes by feeding unblanched Brussels sprouts containing active myrosinase to mice for 2 wk. Robbins MG, Hauder J, Somoza V, Eshelman BD, Barnes DM, Hanlon PR.
  11. BMC Complement Altern Med. 2009 Dec 14;9:51. Aqueous extracts from dietary supplements influence the production of inflammatory cytokines in immortalized and primary T lymphocytes. Hanlon PR, Robbins MG, Scholl C, Barnes DM.
  12. J Agric Food Chem. 2009 Dec 9;57(23):11134-9. Polyacetylene diversity and bioactivity in orange market and locally grown colored carrots (Daucus carota L.). Metzger BT, Barnes DM.
  13. Journal of Functional Foods Volume 1, Issue 4, October 2009, Pages 356-365 Aqueous extract from the vegetative portion of Spanish black radish (Raphanus sativus L. var. niger) induces detoxification enzyme expression in HepG2 cells. Paul R. Hanlon, Melissa G. Robbins, Lori D. Hammon, David M. Barnes
  14. J Med Food. 2009 Aug;12(4):854-60. A comparison of pectin, polyphenols, and phytosterols, alone or in combination, to lovastatin for reduction of serum lipids in familial hypercholesterolemic swine. Metzger BT, Barnes DM, Reed JD.
  15. J Chiropr Med. 2008 Sep;7(3):94-100. A nutritional program improved lipid profiles and weight in 28 chiropractic patients: a retrospective case series. Powell JP, Leonard JS.
  16. J Agric Food Chem. 2008 May 28;56(10):3554-60. Epub 2008 Apr 24. Purple carrot (Daucus carota L.) polyacetylenes decrease lipopolysaccharide-induced expression of inflammatory proteins in macrophage and endothelial cells. Metzger BT, Barnes DM, Reed JD.
  17. J Agric Food Chem. 2007 Aug 8;55(16):6439-46. Epub 2007 Jul 6. Aqueous extract from Spanish black radish (Raphanus sativus L. Var. niger) induces detoxification enzymes in the HepG2 human hepatoma cell line. Hanlon PR, Webber DM, Barnes DM.
  18. J Agric Food Chem. 2007 Jul 25;55(15):6032-8. Epub 2007 Jul 4. Insoluble fraction of buckwheat (Fagopyrum esculentum Moench) protein possessing cholesterol-binding properties that reduce micelle cholesterol solubility and uptake by Caco-2 cells. Metzger BT, Barnes DM, Reed JD.

View all published research

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.