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Ostrophin PMG®

  • Gluten Free

Introduced in 1955

Product # Content Price
6500 90 Tablets $30.00

Ostrophin PMG combines synergistic nutrients for natural bone health support.*

  • Provides a unique profile of minerals, nucleotides, and peptides along with unknown factors
  • Supports healthy bone function*
What is a Protomorphogen™ extract?

Protomorphogen™ extracts are specific material extracted from animal glands and organs through a complex, multistep process to retain what Standard Process founder Dr. Royal Lee termed “cell determinants.”

In 1947, he defined cell determinants as the smallest functional unit of the chromosome, saying that cell determinants are the components that direct, maintain, and regulate cell functions (such as those related to protein, genetic material, and compounds like minerals).

Modern laboratory methods have confirmed that these proprietary extracts contain minerals, nucleotides (the components of nucleic acids like RNA and DNA), and peptides (short chains of amino acids). Lab and clinical investigations into the structure and function of Standard Process animal tissue extracts are ongoing.*

Why is this extract used in Standard Process dietary supplements?

The Protomorphogen™ extraction process utilizes glands and organs because they are inherently different from skeletal muscle. Organ meats have more DNA per gram than skeletal muscle, different protein profiles, and different starting concentrations of vitamins and minerals.1,2,3

Dr. Lee believed that animal extracts support cellular health at the level of the nucleus and provide targeted benefits for cellular function. In an unbalanced system, he believed, gland and organ extracts activate a renewed function of the normal gland.*

How does this product support healthy bone function?

Veal bone PMG™ extract is a complex raw material. This ingredient may distill the complexity of veal bone to support human bone function. For additional benefit, Ostrophin PMG contains ingredients sourced from carrot and sweet potatoes due to their nutritional complexity.*

Both calcium and manganese influence bone integrity and may positively influence bone health.4 Manganese acts as a catalyst and cofactor in many complicated and important enzymatic processes, such as in the synthesis of glycosaminoglycans (GAGs).5 GAG molecules are an important building block in the bone and cartilage structural matrix6 and provide support for ligaments and tendons.7*

  • 1. Honikel, K. O. (2011). Composition and calories. In L.M. L. Nollet, & F. Toldrá (Eds.), Handbook of analysis of edible animal by-products (pp. 105–121). Boca Raton FL, USA: CRC Press.
  • 2. Toldrá, F., Mora, L. and Reig, M. (2016). New insights into meat by-product utilization. Meat Science, 120, pp.54-59.
  • 3. Doreen Gille, Alexandra Schmid; Vitamin B12 in meat and dairy products. Nutr Rev 2015; 73 (2): 106-115. doi: 10.1093/nutrit/nuu011.
  • 4. Zofkova, I., Davis, M., & Blahos, J. (n.d.). Trace elements have beneficial, as well as detrimental effects on bone homeostasis. Retrieved April 18, 2017, from
  • 5.
  • 6. Mathews, S., Mathew, S. A., Gupta, P. K., Bhonde, R. and Totey, S. (2014), Glycosaminoglycans enhance osteoblast differentiation of bone marrow derived human mesenchymal stem cells. J Tissue Eng Regen Med, 8: 143–152. doi:10.1002/term.1507.
  • 7. Ryan, C., Sorushanova, A., Lomas, A., Mullen, A., Pandit, A. and Zeugolis, D. (2015). Glycosaminoglycans in Tendon Physiology, Pathophysiology, and Therapy. Bioconjugate Chemistry, 26(7), pp.1237-1251.

Whole Food Nutrient Solutions

Since 1929, Standard Process has been the visionary leader in whole food nutrient solutions. We apply systems thinking to holistic nutrition that empowers practitioners to transform lives. Dedicated to the whole food philosophy of our founder, Dr. Royal Lee, our goal is to carry on his mission to provide nutrients for the body that are as close as possible to how they are found in nature.

Our products include foods that are prepared in a way that safeguards their nutritional value. The majority of these ingredients are grown locally on our certified organic farm and may require chopping, dicing, juicing, and/or drying for use in our products. The resulting whole food ingredients are then added to a formula that may include whole food extracts, animal tissue extracts and concentrates, botanicals, whole food isolates, and synthetic ingredients. These highly complex combinations contain a variety of elements designed to trigger trophic effects that support the body’s healthy balance and wellness.*


Suggested Use: One tablet per meal, or as directed.

Supplement Facts
Serving Size: 1 Tablet Servings per Container: 90
Amount per Serving %DV
Calories 2  
Calcium 25 mg 2%
Manganese 4 mg 200%
Proprietary Blend: 250 mg Veal bone PMG™ extract†, bovine bone†, carrot (root)†, and sweet potato†.

†Daily Value (DV) not established.

Other Ingredients: Calcium lactate, honey, manganese lactate, and calcium stearate.

Please consult the actual product label for the most accurate product information.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.