Equine Mobility Support
The right ingredients for joint health
You've seen your share of equine joint health supplements. But have you seen one with this combination of ingredients?
Each ingredient in Equine Mobility Support has a specific purpose. Together, they work in a coordinated and systemic manner to support joint and whole-body health. You're getting a unique combination of palatable and pure ingredients, strict product quality-control measures, and proven effectiveness in clinical trials. In short, you're getting a trustworthy alternative to other joint health supplements.
Safe for horses—and humans
We produce Equine Mobility Support on the same manufacturing line as our human health supplements, using the same high-quality ingredients found in our supplements for people. And we test all ingredients extensively. What you see on the label is what's inside the bottle, pure and simple.
Equine Mobility Support:
- Promotes healthy joint function, flexibility and mobility
- Reduces discomfort, inflammation, and lameness
- Supports the repair of joints
- Supplies antioxidants to help protect against free radical damage
Used and recommended by veterinarians and industry professionals, Equine Mobility Support is a whole food supplement that provides support for all equine classes, especially active horses.
A unique combination of ingredients
Glucosamine
Glucosamine is an important component of cartilage growth, maintenance, and repair. While research is ongoing in horses, meta-analysis of human clinical trials has confirmed the value of glucosamine in support of the osteoarthritic patient.1,2,3 In the horse, glucosamine has been implicated in regulation of matrix metalloproteinase expression.4,5
In practice, glucosamine is commonly used to support healthy joints, much the same way that glucosamine is used in humans.
Chondroitin Sulfate
Chondroitin sulfate is an important component of the extracellular matrix of connective tissue. Low molecular weight chondroitin sulfate is bioavailable in the horse, although to a limited degree.6 While the mechanism of chondroitin sulfate action in joint health remains to be determined, it is an important component of compounds found in various functional components of the joint.
Wheat Germ Oil
Wheat germ oil provides a rich source of vitamin E. Vitamin E promotes healthy circulation, enhances athletic performance, and helps reduce muscle cramping. Vitamin E is an important lipophilic antioxidant implicated in a number of physiological functions. Tocopherols support immune function and lessen the inflammatory response by scavenging reactive oxygen species.
Flax Meal
Flax contains significant levels of omega-3 fatty acids, specifically alpha linolenic acid (ALA) and omega-3 fatty acids, which have been implicated in reducing inflammation. Studies have shown that omega-3 fatty acids reduced inflammatory thromboxane and decreased endotoxin-induced TNF production in horses.7,8
Ginger
Ginger contains a broad spectrum of bioactive compounds. Several ginger compounds have well-documented effects on inflammation. For example, 6-gingerol and 6-paradol have both anti-inflammatory and anti-tumor (proliferation) activity, while 8-paradol and 9-shagaol have been shown to inhibit COX-2 activity. This action may explain ginger's historic use as an analgesic.9,10
Cinnamon
Cinnamon is used to mask, in part, the bitter ginger taste, improving palatability. It also makes a great smelling product.
References
- Clegg DO, Reda DJ, Harris CL, et. al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med. 2006; 354:795-808.
- McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA. 2000; 283:1469-1475.
- Towheed TE, Maxwell L, Anastassiades TP, Shea B, Houpt J, Robinson V, Hochberg MC, Wells G. Glucosamine therapy for treating osteoarthritis. Cochrane Database Syst Rev: CD002946; 2005.
- Neil KM, Orth MW, Coussens PM, Chan PS, Caron JP. Effects of glucosamine and chondroitin sulfate on mediators of osteoarthritis in cultured equine chondrocytes stimulated by use of recombinant equine interleukin-1beta. Am J Vet Res. 2005; 66:1861-1869.
- Chan PS, Caron JP, Orth MW. Effect of glucosamine and chondroitin sulfate on regulation of gene expression of proteolytic enzymes and their inhibitors in interleukin-1-challenged bovine articular cartilage explants. Am J Vet Res. 2005; 66:1870-1876.
- Du J, White N, Eddington ND. The bioavailability and pharmacokinetics of glucosamine hydrochloride and chondroitin sulfate after oral and intravenous single dose administration in the horse. Biopharm Drug Dispos. 2004; 25:109-116.
- McCann ME, Moore JN, Carrick JB, Barton MH. Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in vitro. Shock. 2000; 14:222-228.
- Morris DD, Henry MM, Moore JN, Fischer JK. Effect of dietary alpha-linolenic acid on endotoxin-induced production of tumor necrosis factor by peritoneal macrophages in horses. Am J Vet Res. 1991; 52:528-532.
- Surh Y. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res. 1999; 428:305-327.
- Tjendraputra E, Tran VH, Liu-Brennan D, Roufogalis BD, Duke CC. Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells. Bioorg Chem. 2001; 29:156-163.